Browsing by Author "Johnson, Arthur E."
Now showing items 1-20 of 20
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Cargill, Holly Beth (Texas A&M University, 2006-08-16)Most proteins residing in the mitochondrial matrix are synthesized in the cytosol and post-translationally imported into the mitochondrial matrix. The matrix-targeted preproteins traverse the outer mitochondrial membrane ...
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McLean, Janel Renee (2009-05-15)Defining the intrinsic properties of amino acids which dictate the formation of helices, the most common protein secondary structure element, is an essential part of understanding protein folding. Pauling and co-workers ...
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Seo, Jeongmin (Texas A&M University, 2006-04-12)Correct localization of lipidated cytosolic proteins to the plasma membrane (PM) is mediated by interactions between lipid anchors of proteins and cell membranes. Previously, dietary fish oil and its major n-3 polyunsaturated ...
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Etchells, Stephanie Anne (Texas A&M University, 2004-11-15)TRiC (TCP-1 ring complex), a type II chaperonin, facilitates protein folding, and we previously showed that TRiC crosslinks to ribosome-bound actin and luciferase nascent chains. Here, it was found that actin and luciferase ...
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Wahlman, Judit (2009-05-15)Secretory proteins that are unable to assemble into native proteins in the endoplasmic reticulum (ER) are transported back into the cytosol for degradation. Many cytosolic and ER resident proteins have been identified so ...
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McCallum, Christine D.; Do, Hung; Johnson, Arthur E.; Frydman, Judith (The Journal of Cell Biology, 2000)
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McCormick, Peter Joseph (Texas A&M University, 2005-02-17)During co-translational integration, the transmembrane (TM) sequence of a nascent membrane protein moves laterally into the ER lipid bilayer upon reaching the translocon. Our lab has previously shown that this movement ...
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Quinlan, Robert Jason (Texas A&M University, 2005-02-17)Protein-ligand and protein-protein interactions are critical to cellular function. Most cellular metabolic and signal tranduction pathways are influenced by these interactions, consequently molecular level understanding ...
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Alder, Nathan N.; Shen, Ying; Brodsky, Jeffrey L.; Hendershot, Linda M.; Johnson, Arthur E. (The Journal of Cell Biology, 2005)
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Nilsson, IngMarie; Kelleher, Daniel J.; Miao, Yiwei; Shao, Yuanlong; Kreibich, Gert; Gilmore, Reid; von Heijne, Gunnar; Johnson, Arthur E. (The Journal of Cell Biology, 2003)
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Higgins, Kelly Jean (Texas A&M University, 2007-09-17)Vascular endothelial growth factor receptor-2 (VEGFR2) is a key angiogenic factor, and angiogenesis is an important physiological process associated with neovascularization, growth, and metastasis of many different tumors. ...
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Jung, Yunhee (Texas A&M University, 2006-08-16)The cavity within the transmembrane staphylococcal α-hemolysin (αHL) pore is roughly a sphere of diameter ~45 Ã (volume ~32,600 Ã 3). The alpha-hemolysin gene was modified to introduce exogenous polypeptide ...
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Ortigosa, Allison Dawn (Texas A&M University, 2004-09-30)Phosphofructokinase from Bacillus stearothermophilus (BsPFK) is a homotetrameric enzyme with an average of one active site and one allosteric site per subunit. BsPFK is inhibited by phosphoenolpyruvate (PEP) and how this ...
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Saksena, Suraj (Texas A&M University, 2006-04-12)The current "diffusion-retention" model for protein trafficking to the inner nuclear membrane (INM) proposes that INM proteins diffuse laterally from the membrane of the endoplasmic reticulum into the INM and are then ...
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Stammler, Suzanne (2010-10-12)The biological function of RNA is often linked to an ability to adopt one or more mutually exclusive conformational states or isomers, a characteristic that distinguishes this biomolecule from proteins. Two examples of ...
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Ramachandran, Rajesh (Texas A&M University, 2006-04-12)Perfringolysin O (PFO), a cytolytic toxin from by the pathogenic bacterium Clostridium perfringens, perforates mammalian cell membranes by forming large aqueous pores. Secreted as water-soluble monomers, the toxin molecules ...
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Sobrado, Pablo (Texas A&M University, 2004-09-30)Flavocytochrome b2 catalyzes the oxidation of lactate to pyruvate. Primary deuterium and solvent kinetic isotope effects have been used to determine the relative timing of cleavage of the lactate OH and CH bonds by the ...
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Williamson, Shawn T (Texas A&M University, 2006-10-30)The amino-terminal 33 amino acids of the baculovirus integral membrane protein, ODV-E66, are sufficient for localization of fusion proteins to viralinduced intranuclear microvesicles (MV) and occlusion derived virus ...
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Lin, Pen-Jen; Jongsma, Candice G.; Liao, Shuren; Johnson, Arthur E. (The Journal of Cell Biology, 2011)
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Davis, Alison J.; Sepuri, Naresh B.; Holder, Jason; Johnson, Arthur E.; Jensen, Robert E. (The Journal of Cell Biology, 2000)